Champions Buriram got off to a winning start with a 2-1 home win over Ratchaburi. The game burst into life in the second-half with two goals in seven minutes by Jakkaphan and Diogo for the home side before Menezes pulled one back from the penalty spot.
Muang Thong came back from two goals down at Bangkok United to win 3-2, Samphaodi netting a hat-trick.
Thai Port had a comfortable 3-0 home victory over ten-man Pattaya and Nakhon Ratchasima saw off Bangkok Glass at home with a late Rittiphan strike.
Another late goal gave Navy a 1-0 home victory over Ubon and Chainat Hornbill and Suphanburi played out a goalless draw.
Chiang Rai had a narrow 1-0 home win over Chonburi and Sukhothai won 2-1 at Air Force with Bonilla scoring twice for the visitors.
New boys Prachuap kicked off with a 3-2 home win over Police Tero in an entertaining encounter.
P W D L F A Pts
| 1 | Port | 1 | 1 | 0 | 0 | 3 | 0 | +3 | 3 | W | ||
| 2 | Muang Thong United | 1 | 1 | 0 | 0 | 3 | 2 | +1 | 3 | W | ||
| 3 | Prachuap | 1 | 1 | 0 | 0 | 3 | 2 | +1 | 3 | W | ||
| 4 | Buriram United | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W | ||
| 5 | Sukhothai | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W | ||
| 6 | Chiangrai United | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W | ||
| 7 | Nakhon Ratchasima | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W | ||
| 8 | Navy | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W | ||
| 9 | Chainat Hornbill | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | D | ||
| 10 | Suphanburi | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | D | ||
| 11 | Bangkok United | 1 | 0 | 0 | 1 | 2 | 3 | -1 | 0 | L | ||
| 12 | Police Tero | 1 | 0 | 0 | 1 | 2 | 3 | -1 | 0 | L | ||
| 13 | Air Force Central | 1 | 0 | 0 | 1 | 1 | 2 | -1 | 0 | L | ||
| 14 | Ratchaburi | 1 | 0 | 0 | 1 | 1 | 2 | -1 | 0 | L | ||
| 15 | Bangkok Glass | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L | ||
| 16 | Chonburi | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L | ||
| 17 | Ubon UMT | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L | ||
| 18 | Pattaya United | 1 | 0 | 0 | 1 | 0 | 3 | -3 | 0 | L |